Preoperative Short-Course Radiotherapy in Locally Advanced Rectal Cancer: The Attitude on How to Use Radiotherapy in Rectal Cancer is Changing

Preoperative short-course radiotherapy in locally advanced rectal cancer: the attitude on how to use radiotherapy in rectal cancer is changing.

An Update on Preoperative Radiotherapy for Locally Advanced Rectal Cancer

Even in patients undergoing an optimal surgical technique (e.g., total mesorectal excision), radiotherapy provides a significant benefit in the local control of rectal cancer. Compared with postoperative treatment, chemoradiotherapy given preoperatively has been shown to decrease local recurrence rates and toxicity. Additionally, preoperative chemoradiotherapy permits the early identification o...

Intraoperative Radiotherapy for Locally Advanced Rectal Cancer

PURPOSE Although intraoperative radiotherapy (IORT) is known to be a method that can reduce local recurrence in locally advanced colorectal cancer, it is not widely used. The aim of this study was to report our experience with IORT for locally advanced rectal cancer. METHODS From 1991 to 1994, nine patients with locally advanced rectal cancer received IORT. External beam radiotherapy was give...

Preoperative radiotherapy "short course" in rectal cancer in elder patient: low impact on tumor regression

Upfront systemic chemotherapy and preoperative short-course radiotherapy with delayed surgery for locally advanced rectal cancer with distant metastases

BACKGROUND Choosing the most effective approach for treating rectal cancer with mesorectal fascia (MRF) involvement or closeness and synchronous distant metastases is a current clinical challenge. The aim of this retrospective study was to determine if upfront systemic chemotherapy and short-course radiotherapy (RT) with delayed surgery enables R0 resection. METHODS Between March 2009 and Oct...